What is TuttleNumbNow?

TuttleNumbNow (TNN) is changing forever the way dentistry is practiced. TNN is a revolution, a complete rethinking and retraining of local anesthesia, introduced by Dr. Gregory K. Tuttle.

The system includes a new primary intraossous injection for lower posterior teeth minimizing use of the IA nerve block. We know that for some teeth a simple infiltration is adequate, but if a tooth requires more, we’ve developed a step-by-step protocol for local anesthesia.

The TuttleNumbNow system is designed for the most experienced dentist and specialist, down to the recent dental graduate or hygienist. Join us in practicing the most innovative, cost-effective approach to dental anesthesia.

Why TuttleNumbNow?

FOR TOUGH-TO-NUMB TEETH

With TuttleNumbNow, we start with the shot that works best. We give you the most direct way to numb a tooth with the least amount of anesthetic, all in the least painful way. We teach you 10 easy steps to a new primary injection for lower molars.

AN ANSWER FOR EVERY TOOTH, EVERY TIME

You won’t get stuck wondering what to do if your first injection doesn’t work. With the TuttleNumbNow TNN 10 Shot Protocol you’re guided step by step. With our system, Dr. Tuttle gives you the precise injection site, type, needle, drug, vasoconstrictor, and dose for your patient.

RENEW YOUR LOVE OF DENTISTRY

The TuttleNumbNow system takes the guesswork out of anesthesia so you can take control of your patient’s pain. The technique has been refined by the leading researchers, manufacturers and educators of the dental world. Many have chosen TNN as the primary injection of choice for lower molars and protocol for every tooth.

FOR TOUGH-TO-NUMB TEETH

With TuttleNumbNow, we start with the shot that works best. We give you the most direct way to numb a tooth with the least amount of anesthetic, all in the least painful way. We teach you 10 easy steps to a new primary injection for lower molars.

AN ANSWER FOR EVERY TOOTH, EVERY TIME

You won’t get stuck wondering what to do if your first injection doesn’t work. With the TuttleNumbNow TNN 10 Shot Protocol you’re guided step by step. With our system, Dr. Tuttle gives you the precise injection site, type, needle, drug, vasoconstrictor, and dose for your patient.

RENEW YOUR LOVE OF DENTISTRY

The TuttleNumbNow system takes the guesswork out of anesthesia so you can take control of your patient’s pain. The technique has been refined by the leading researchers, manufacturers and educators of the dental world. Many have chosen TNN as the primary injection of choice for lower molars and protocol for every tooth.

What is in the kit

The kit includes everything you need to get started:

1. The Right Tools
Recommended needles, IncreMental Syringe, and TNN needle guides

2. Reference Materials
An instructional booklet for easy reference

3. Over 40 Minutes of In-Depth Training Videos
Helps explain the TuttleNumbNow technique and protocol in full detail

4. CE Credits
Once you complete the TuttleNumbNow training, there is a code to earn 2 ADA CERP Continuing Education Credits

It's all about the patient

Going to the dentist can be an awful experience for some patients. With TuttleNumbNow the goal is no numb lip, no numb tongue, and you can work in all four quadrants without rescheduling patients for multiple visits. It eliminates frustration for both the dentist and the patient! 

Find a TNN Dentist

As the news of TuttleNumbNow spreads, we often get asked by patients if there is a TNN dentist nearby.

We've created an interactive map of those trained in TuttleNumbNow, so now patients can find you!

Get noticed by patients with an upgraded listing through our Premier TNN Annual Registry!

The world needs TuttleNumbNow

Dentists in remote locations work out of one chair with limited dental supplies. The TuttleNumbNow system is a global system and has dramatically impacted third world countries for the better. We’ve had dentists in all 50 states and more than 28 countries throughout the world embrace the system. You can now accomplish much more with much less.

"This will change your life"
– Denise D.
"TNN was a huge success for this difficult situation and saved the patient the expense and complexity of general anesthesia."
- Jim C. DDS
“Maybe the most beneficial, stress reducing thing I've ever done…”
– Jim
“I could now confidently shorten these appointments by 15–30 minutes and still stay on time.”
– Dr. Bryan T.
Slideshow
Tell your story with images

TuttleNumbNow News & Events

UNMC Pediatric Dental School Residents Learn TNN

Big thanks to the University of Nebraska Medical Center Pediatric Dentistry Clinic and residents for inviting us out to train your providers.
This technique is a complete game changer for kids!

Their bone is much easier to penetrate and children especially like leaving the dentists without a numb face! We are changing the future of dentistry… one school at a time!

New Study Published about TNN - Journal of Dental Anesthesia and Pain Medicine

New study published about TuttleNumbNow in J Dent Anesth Pain Med. 2026 April. 

Efficacy of the TuttleNumbNow anesthesia protocol for mandibular first molars: a retrospective study

Inferior alveolar nerve block (IANB) is the standard anesthetic approach for mandibular first molars; however, it has well-documented limitations, including variable success rates, delayed onset, higher anesthetic dose requirements, and potential complications. The TuttleNumbNow (TNN) anesthesia protocol introduces intraosseous (IO) injections as the primary anesthetic modality, followed by infiltration and IANB as a last resort. This approach seeks to provide rapid site-specific anesthesia at reduced pharmacological doses. This study evaluated the clinical efficacy of the TNN protocol for mandibular first molar procedures in a private practice setting.

Hands-On in Manti

One of the best ways to learn TuttleNumbNow is to jump in and try it! We offered a successful hands-on training to Manti dentists hosted by Dr. Rich Carlisle at Manti Family Dental. 

TuttleNumbNow Thanks Industry Leaders

Leaders in the dental industry have helped develop, advance, or promote our training. Find out why.

Get Your TNN Products Today!