STUDIES
Please reach out if you are interested in performing any research or clinical studies regarding TuttleNumbNow. We are happy to help in any way.
Below is a list of related studies:
- Intraosseous (IO) injections allows placement of local anesthetic solution directly into the cancellous bone adjacent to the tooth to be anesthetized
- Reader, Alfred, John Nusstein, and Melissa Drum. Successful local anesthesia for restorative dentistry and endodontics. Quintessence Publishing Company Incorporated, 2017.p.132
- http://www.stomaeduj.com/wp-
content/uploads/2018/01/Book_ rev_2_v5_1.pdf - Scalpel Designed Bevel Studies- a significant lower pain level was found in Scalpel Bevel
- M. Dau, I. Buttchereit, C. Ganz, B. Frerich, E.N. Anisimova, M. Daubländer, P.W. Kämmerer, Influence of needle bevel design on injection pain and needle deformation in dental local infiltration anaesthesia – randomized clinical trial, International Journal of Oral and Maxillofacial Surgery,Volume 46, Issue 11,2017,Pages 1484-1489ISSN 0901-5027
- https://www.sciencedirect.com/
science/article/abs/pii/ S0901502717315217 - 50 years since new local anesthesia technique was invented by Gow Gates with an alternative to the IA Nerve Block
- Isen, David. "FEATURES-PRODUCT PROFILE-A New Method for Intraosseus Injection: The X-Tip." Oral Health 90.7 (2000): 44-46.
- https://www.oralhealthgroup.
com/features/product-profile- a-new-method-for-intraosseus- injection-the-x-tip/ - Needle Gauge Length
- Webb, Laura J. "Orabloc®."
- https://www.orabloc.com/wp-
content/uploads/Tip-Selecting- the-right-needle.pdf - Needle Bending Study-
- Tuttle JJ, Davidson AD, Tuttle GK. Bending 30-gauge needles using a needle guide: fatigue life evaluation. J Dent Anesth Pain Med. 2023 Oct;23(5):281-285.
- https://jdapm.org/DOIx.php?id=
10.17245/jdapm.2023.23.5.281 - For a “hot tooth” with symptomatic irreversible pulpitis (SIP), an IAN is only 64% effective
- Reader, Successful Local Anesthesia: What Endodontists Need to Know, 2017
- Reader A, Nusstein J, Drum M. Successful Local Anesthesia for Restorative Dentistry and Endodontics, Quintessence Publishing Co, Inc. Hanover Park, IL. 2011, p 34, 133, 134, 135, 138, 139, 140, 159.
- https://www.aae.org/specialty/
successful-local-anesthesia- what-endodontists-need-to- know/ - The IAN not only falls short statistically in dental local anesthesia, but also among all local anesthetic blocks in medicine
- Advantageous to find an alternative simple technique
- Thangavelu, K., R. Kannan, and N. Senthil Kumar. "Inferior alveolar nerve block: Alternative technique." Anesthesia, essays and researches 6.1 (2012): 53.
- https://www.ncbi.nlm.nih.gov/
pmc/articles/PMC4173425/ - TuttleNumbNow Intraosseous injection comparison with buccal infiltration for pulpal anesthesia in mandibular first molars.
- Efficacy of the TuttleNumbNow Intraosseous Method for Pulpal Anesthesia in the Mandibular First Molar: A Prospective, Randomized, Crossover Study
- https://pubmed.ncbi.nlm.nih.gov/38266911/
- Increased Anesthetic Requirement in Individuals with Red Hair: Phenotypic and Genotypic Correlation
- Red hair appears to be a distinct phenotype linked to anesthetic requirement in humans that can also be traced to a specific genotype.
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1362956/
